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Updated: Sep 3, 2026

Candida albicans Biofilm Chip CaBChip for High-throughput Antifungal Drug Screening
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虚拟查辅助识别植物化合物作为强大的抑制剂对抗Candida lusitaniae;一个in-silico研究

Rimsha Timotheous1, Habiba Naz1, Usman Arif2

  • 1Department of Biotechnology, Knowledge Unit of Science (KUSC), University of Management and Technology (UMT) Sialkot Campus, Sialkot, Pakistan.

BMC infectious diseases
|January 6, 2025
PubMed
概括

戴津4'0-葡萄化物显示出作为一种新的抗真菌药物对抗Candida lusitaniae的承诺. 这种植物化学物质在体中表现出优异的结合和类似药物的特性,这表明它有可能治疗严重的真菌感染.

关键词:
C. 卢西塔尼亚 (C. lusitaniae) 是一种植物.分子对接分析分子对接分析植物化学品 植物化学品分泌的阿斯巴提尔蛋白酶 (SAP)虚拟选是一个虚拟的选.

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相关概念视频

Antifungal Agents01:15

Antifungal Agents

Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to cholesterol contributes to...