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Updated: Jun 29, 2026

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
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用于预测乳腺癌新辅助化疗治疗中的治疗反应和毒性而进行血清代谢分析:一项追溯纵向研究

Zhihao Fang1,2, Guohong Ren1,2, Shouyu Ke1,2

  • 1Department of Breast Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Jiefang Road, Hangzhou, Zhejiang, China.

Breast cancer research : BCR
|January 6, 2025
PubMed
概括

血清中的代谢物变化,特别是氨基酸和脂通路的代谢物变化,可以预测接受新辅助化疗 (NACT) 的局部晚期乳腺癌患者的治疗反应和毒性. 这突显了个性化NACT战略的潜力.

关键词:
乙卡尼丁是一种乙卡尼丁.乳腺癌 乳腺癌 乳腺癌重要的氨基酸是必不可少的.代谢学 代谢学 代谢学新辅助化学疗法新辅助化学疗法血清的血清是什么意思

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...