母猪的阴道和肠道微生物群与寿命和生殖能力相关
Ziyu Liu1, Tsungcheng Tsai1, Bin Zuo1
1Department of Animal Science, University of Arkansas, Fayetteville, AR, USA.
Journal of animal science and biotechnology
|January 6, 2025
概括
母猪的直肠和阴道微生物群影响生殖寿命. 像Akkermansia和Lactobacillus这样的特定细菌与种子的长寿和繁殖成功在多个平价上有关.
科学领域:
- 动物科学动物科学
- 微生物组研究 微生物组研究
- 生殖生物学 生殖生物学
背景情况:
- 猪产业的生长寿命和生殖性能对于猪产业至关重要.
- 关于母猪微生物组与生殖寿命之间的联系的了解有限.
研究的目的:
- 调查直肠和阴道微生物组与母猪生殖寿命之间的关联.
- 为了确定母猪繁殖成功的微生物预测因素,在多个平价范围内.
主要方法:
- 收集并测序了48头母猪的直肠和阴道抽样.
- 利用RandomForest分析在早期繁殖阶段识别微生物预测因素.
- 对微生物组变化的纵向跟踪在四个平价上进行.
- 采用LEfSe分析来识别与平价相关的细菌.
主要成果:
- 确定了与母猪寿命相关的关键细菌 (例如,Akkermansia,Lactobacillus).
- 在长寿母猪中观察到氨基酸生物合成中的预测KEGG基因丰度下降.
- 具有特征的纵向微生物群转移和与平价相关的细菌 (例如,链球菌,乳杆菌,Veillonella).
- 发现的细菌预测因子 (例如,Prevotellaceae NK3B31组) 总出生小猪.
结论:
- 在繁殖寿命较长的母猪中,直肠和阴道微生物组的组成在均等性之间发生显著变化.
- 特定的细菌与生殖寿命,均等性和整体生殖表现有关.
- 这些发现为微生物组调节策略提供了基础,以提高猪产量.
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