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Updated: Jun 3, 2025

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无内毒素的外膜囊泡用于安全和模块化的抗癌免疫疗法.

Mei-Yi Chen1,2,3, Ting-Wei Cheng1,2, Yi-Chung Pan1,2

  • 1Chemical Biology and Molecular Biophysics Program, Taiwan International Graduate Program, Academia Sinica, No. 128, Sec. 2, Academia Rd., Nangang (Nankang) Dist., Taipei City 115201, Taiwan.

ACS synthetic biology
|January 7, 2025
PubMed
概括

从细菌外膜囊泡 (OMVs) 中去除脂聚糖 (LPS) 显著提高了它们的安全性和抗癌疗效. 与传统的OMV相比,没有LPS的OMV表现出更好的耐受性和优越的瘤抑制作用.

关键词:
细菌工程 细菌工程 工程免疫疗法 免疫疗法脂多糖 (LPS) 是一种脂多糖.纳米颗粒是一种纳米粒子.外膜囊泡 (OMV) 是一种外膜囊泡.

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