老年患者手术前功能与结的组成之间的相关性:回顾性分析
Xiuxiu Wang1, Naifen Xu2, Mengjie Xu3
1Department of Laboratory Medicine, The People's Hospital of Pingyang, 325400 Wenzhou, Zhejiang, China.
Archivos espanoles de urologia
|January 7, 2025
概括
老年患者的石组成因功能而异. 异常的功能与更多的尿酸结石和较少的酸盐结石有关,影响治疗策略.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 老年医学 老年医学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 结石疾病是老年人的重要健康问题.
- 手术前的功能可能会影响结石的组成和治疗.
- 了解这种关系可以优化老年结石患者的治疗策略.
研究的目的:
- 调查老年患者手术前功能与结石组成之间的相关性.
- 为了确定功能受损是否影响老年人形成的结石类型.
- 为调整老年人结石的管理方法提供见解.
主要方法:
- 对1154名因结石住院的老年患者 (≥60岁) 的回顾性队列研究 (2021年1月至2023年12月).
- 患者分为正常 (估计的淋巴膜过率[eGFR]≥90毫升/分钟/1.73米) 和异常 (eGFR<90毫升/分钟/1.73米) 的功能组.
- 通过红外光谱学分析结石的组成;收集人口,石头和生物化学数据.
主要成果:
- 与正常功能 (n=251) 相比,功能异常 (n=251) 与尿酸结石的发病率较高 (11.16%与6.76%,p=0.029) 和氧化结石的发病率较低 (42.63%与51.50%,p=0.016) 相关.
- 患有功能异常的患者表现出显著增加的血清肌素和尿素水平,以及较低的EGFR.
- 生物化学概况显示出显著差异,功能异常与较差的功能标志物有关.
结论:
- 手术前的功能显著影响老年患者的结石组成.
- 老年人功能受损与尿酸结石的患病率增加有关.
- 这些发现表明,在老年人治疗结石时,需要考虑功能,特别是在结石成分方面.
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