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Updated: Jun 3, 2025

Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair
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Published on: May 24, 2017

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聚胺吸附剂与AP位点:与DNA聚合酶和AP内核酶的相互作用

Anna V Yudkina1, Margarita M Amanova1, Dmitry O Zharkov1,2

  • 1SB RAS Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentieva Avenue, Novosibirsk 630090, Russia.

Chemical research in toxicology
|January 7, 2025
PubMed
概括

生物多氨酸在DNA的apurinic/apyrimidinic (AP) 位点形成 adducts,可能阻断DNA复制和转录. 虽然一些酶可以修复这些添加物,但修复通常是缓慢的,突出显示了一种新的DNA损伤途径.

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