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Updated: May 7, 2025

A Standard Methodology to Examine On-site Mutagenicity As a Function of Point Mutation Repair Catalyzed by CRISPR/Cas9 and SsODN in Human Cells
10:07

A Standard Methodology to Examine On-site Mutagenicity As a Function of Point Mutation Repair Catalyzed by CRISPR/Cas9 and SsODN in Human Cells

Published on: August 25, 2017

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抗基因寡核酸塞侵入dDNA并降低huntingtin的表达

Tea Umek1,2,3, Karin E Lundin1, Metoboroghene O Mowoe1,2,4

  • 1Department of Laboratory Medicine, Karolinska Institutet, ANA Futura, Alfred Nobels Allé 8, 14152 Huddinge, Stockholm, Sweden.

Molecular therapy. Nucleic acids
|January 7, 2025
PubMed
概括

用锁定核酸-DNA混合器和间隔部分修改的抗基因寡核酸有效地侵入目标DNA. 这些化合物通过降低患者细胞中特定基因表达的调节来显示基因调节疗法的前景.

关键词:
侵入DNA链的寡核化物.针对DNA的向定位HTT HTT 这样就好了.亨廷顿病就是亨廷顿病.MT:寡核酸:治疗方法和应用.我的世界 MYC抗基因寡核酸的抗基因基因表达的基因表达方式锁定核酸的核酸被锁定.酸酸是一种酸.形成三倍体的寡核酸形成三倍体

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