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在结直肠癌瘤中,体质微卫星的不稳定性,高突变状态和特定的T细胞子集之间的关联

Claire E Thomas1, Yasutoshi Takashima2, Evertine Wesselink3

  • 1Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, United States.

Frontiers in immunology
|January 7, 2025
PubMed
概括

微卫星不稳定性高的结直肠癌显示T细胞透率增加,特别是CD8+T细胞. 这一发现可能有助于识别那些对免疫治疗有反应的患者.

关键词:
修复DNA不匹配的修复在T细胞,T细胞.结肠直肠癌是什么意思皮质上皮质上皮质上皮质.过度突变是一种超级突变.微卫星的不稳定性分子流行病学分子流行病学树木的树干结构

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