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Updated: Jun 3, 2025

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain
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Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain

Published on: October 25, 2016

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一个以为中心的TCR模仿结合模块的De novo设计和结构

Karsten D Householder1,2, Xinyu Xiang1, Kevin M Jude1

  • 1Department of Molecular and Cellular Physiology, Stanford University School of Medicine; Stanford, CA 94305 USA.

bioRxiv : the preprint server for biology
|January 7, 2025
PubMed
概括

我们开发了一种新的T细胞受体 (TCR) 模仿器,用于精确的癌症免疫治疗. 这种模拟器以高特异性的瘤抗原为目标,提供了潜在的新治疗策略.

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Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay19:05

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Overview
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Naive T cells that have not yet encountered an antigen express two primary CD...
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