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Updated: Jun 3, 2025

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在内分泌抵抗性雌激素受体阳性乳腺癌中的代谢开关

Heather M Brechbuhl1, Amy Han1, Kiran Vinod Paul1

  • 1Department of Medicine, Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado USA.

bioRxiv : the preprint server for biology
|January 7, 2025
PubMed
概括

丁甲基烟酸 (DMF) 可以通过纠正代谢中断,特别是TCA循环中,恢复对耐受性雌激素受体阳性乳腺癌的内分泌疗法的敏感性,如他莫西芬和富尔韦斯特兰特. 这种方法为克服内分泌抵抗提供了一个新的策略.

关键词:
乳腺癌 乳腺癌 乳腺癌内分泌电阻是内分泌的抵抗.雌激素受体的受体代谢过程中的代谢.

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