野生子肠道微生物群的季节和社会群体之间的真核生物组成
Mary Chege1,2,3, Pamela Ferretti4, Shasta Webb3
1One Health Centre, Kenya Institute of Primate Research, Nairobi, Kenya.
bioRxiv : the preprint server for biology
|January 7, 2025
概括
幼核性肠道微生物,包括原生体和真菌,在野生中很常见. 社会群体显著影响真核细胞肠道微生物组的组成,突出其对灵长类健康的重要性.
科学领域:
- 微生物学 微生物学
- 细胞微生物学的微生物学
- 灵长类微生物组研究
背景情况:
- 动物微生物组包括细菌,病毒和真核生物 (真菌,原生虫,虫).
- 与细菌和病毒组成部分相比,动物微生物群中的真核微生物多样性尚未得到充分研究.
- 这项研究调查了野生肠道微生物群中的真核生物多样性.
研究的目的:
- 为了描述野生的便样本中的真核生物多样性.
- 为了确定宿主社会群体,性别,年龄或季节是否影响真核细胞社区组成.
- 为了确定肠微生物群中普遍存在的真核生物物种.
主要方法:
- 从肯尼亚73只野生的75个便样本中进行了枪支元基因组测序.
- 对DNA的分析以识别Protista,Chromista和真菌王国中的真核成员.
- 统计分析,以评估宿主因素对真核生物群体结构的影响.
主要成果:
- 在90.7%,46.7%和20.3%的样本中分别检测到Protista,Chromista和真菌.
- 社会群体的成员身份解释了112.2%的真核肠物种组成变化.
- 常见的原生菌包括大肠杆菌和人类肠杆菌;常见的真菌包括Pichia manshurica.
结论:
- 单核微生物 (Protista,Chromista,真菌) 是野生肠道微生物组的组成部分.
- 主体社会群体是肠道真核细胞社区结构的重要预测因素.
- 对灵长类肠道真核生物的进一步研究对于健康监测和管理至关重要.
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