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Updated: Jun 3, 2025

Quantitative Determination of De Novo Fatty Acid Synthesis in Brown Adipose Tissue Using Deuterium Oxide
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甘-3-酸盐激活了CHREBP,FGF21转录和代在素缺乏症中

Vinod Tiwari1, Byungchang Jin2, Olivia Sun1

  • 1Beckman Research Institute of City of Hope; Duarte, USA.

bioRxiv : the preprint server for biology
|January 7, 2025
PubMed
概括

素缺乏 (SLC25A13损失) 导致甘-3-酸盐的积累,激活ChREBP. 这导致FGF21的产生,抑制甜食/酒精摄入量,促进脂质生成,导致肝病.

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