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Updated: Jun 3, 2025

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
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Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities

Published on: July 29, 2014

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一个阿片类药物疗效开关,用于对外围镇痛的可逆光学控制

Luca Posa, Giovanna Romano, Xiang Ji

    bioRxiv : the preprint server for biology
    |January 7, 2025
    PubMed
    概括

    研究人员开发了阿佐-吗啡-3 (AM-3),一种光激活的药物,向片受体 (MORs). 这项创新允许精确的光学控制缓解疼痛,最大限度地减少与传统阿片类药物相关的副作用和过量风险.

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