雷米马佐拉姆对手术内前额阿尔法带功率频谱密度和手术后认知功能的影响 老年人接受下肢骨折手术:一项随机对照试验
Hao Wu1, Shunping Tian1, Hongxia Ma2
1Department of Anesthesiology, The Affiliated Hospital of Yangzhou University, Yangzhou, 225012, People's Republic of China.
Clinical interventions in aging
|January 7, 2025
概括
雷米马佐拉姆在手术期间增加了前额α带活性,从而使老年人接受下肢骨折修复的术后认知功能得到改善. 这表明,雷米马佐拉姆可能有助于预防麻醉后认知能力下降.
科学领域:
- 麻醉学 麻醉学
- 神经科学是一个神经科学.
- 老年病的医生 老年病的医生
背景情况:
- 低脑电图α频段功率与外科手术期间的认知功能障碍有关.
- 关于雷马佐拉姆对老年患者手术前大脑活动和认知结果的影响的研究有限.
研究的目的:
- 调查雷米马佐拉姆对外科手术内额头α带活性的影响.
- 评估雷米马佐拉姆对接受下肢骨折手术的老年人术后认知功能的影响.
主要方法:
- 随机对照试验比较雷米马佐拉姆 (R组) 和米达佐拉姆 (M组) 在下肢骨折的老年人中进行麻醉.
- 在整个手术过程中,脑电图 (EEG) 监测前额α频段功率频谱密度.
- 在手术前和手术后的1,3,5和7天进行认知功能评估.
主要成果:
- 与米达佐拉姆相比,雷米马佐拉姆组显示出明显更高的手术内前额α频段功率光谱密度.
- 雷米马佐拉姆组经历了术后认知功能障碍的发生率显著降低.
结论:
- 雷米马兰在麻醉期间增强了前额α频段功率频谱密度.
- 雷米马佐拉姆可以改善下肢骨折手术的老年患者的术后认知功能.
关键词:
在阿尔法频段的阿尔法频段.这种类型的 benzodiazepines.大脑的波浪,大脑的波浪.认知功能障碍 认知功能障碍年长的老人老年人老年人.神经心理测试 神经心理测试雷米马佐拉姆 (Remimazolam) 是一种药物.更多相关视频
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