慢性病选择性查的预测性诺姆图:一个基于人口的研究
Nghia H Vo1, Bui V Pham2, Nghia N Nguyen1
1Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam.
Canadian journal of kidney health and disease
|January 7, 2025
概括
慢性病 (CKD) 影响越南成年人的13.1%. 年龄,高血压和糖尿病是关键预测因素,使得针对这种常见疾病进行有针对性的查.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 慢性病 (CKD) 是一个重要的全球健康问题,与增加的残疾,降低生活质量和死亡率有关.
- 许多CKD病例在早期无症状,导致诊断和治疗延迟.
- 早期检测和风险分层对于管理CKD进展及其并发症至关重要.
研究的目的:
- 为了确定越南成年人口中CKD的患病率.
- 开发一个预测模型和名谱来识别患有CKD风险的个体.
- 为越南的有针对性的查策略提供见解.
主要方法:
- 这是一项基于人口的横截面研究,涉及1490名越南成年人 (533名男性,957名女性).
- 使用CKD-EPI 2009方程,根据专利蛋白与肌素的比率和/或估计的球过率 (eGFR) 进行CKD诊断,遵循KDIGO 2012指南.
- 贝叶斯模型平均值被用来确定CKD的最佳预测模型.
主要成果:
- 结核病的总体患病率为13.1% (95% CI:11.6-14.6%),女性 (13.8%) 的患病率高于男性 (11.8%).
- 对CKD的最佳预测模型包括年龄,高血压和糖尿病.
- 关键预测因素是年龄 (每5年增加的OR为1.19),高血压 (OR为2.08) 和糖尿病 (OR为1.69). 该模型的预测精度 (AUC) 为0.7.7.
结论:
- 在越南成年人中,CKD是一种常见的疾病.
- 结合年龄,高血压和糖尿病的简化预测模型可以有效地识别需要选择性CKD查的个人.
- 这些发现支持在越南开发针对性公共卫生干预措施,以预防和管理CKD.
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