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Updated: Jun 3, 2025

Aip1p Dynamics Are Altered by the R256H Mutation in Actin
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Published on: July 30, 2014

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胺A C端片段通过抑制蛋白质降解来调节Orai1的表达

Alvaro Macias-Díaz1, Joel Nieto-Felipe1, Isaac Jardín1

  • 1Department of Physiology (Cellular Physiology Research Group), Institute of Molecular Pathology Biomarkers (IMPB), University of Extremadura, Caceres, Spain.

American journal of physiology. Cell physiology
|January 7, 2025
PubMed
概括

在结肠癌中,calpain通过filamin A (FLNA) 裂变增强了C端片段,促进了Orai1和STIM1的表达和储存的进入 (SOCE). 这个片段稳定了Orai1α和STIM1,揭示了一个新的SOCE监管机制.

关键词:
在这里,FLNA FLNA FLNA.这里是Orai1αα.这里是Orai1ββ.在商店经营的Ca2+入口.

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