后鼻神经冷解后鼻复发:一个多中心队列研究
John R Craig1, Curtis Mack2, Aleks Vidovich1
1Department of Otolaryngology-Head and Neck Surgery, Henry Ford Health, Detroit, Michigan, U.S.A.
The Laryngoscope
|January 7, 2025
概括
后鼻神经 (PNN) 的冷藏治疗有效地治疗慢性鼻炎 (CR) 症状,但清晰的细鼻 (CTR) 经常复发. 大多数患者在5个月内会出现令人烦的复发,需要进一步治疗.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 鼻科 鼻科是指鼻科的专家.
- 最少侵入性手术的方法
背景情况:
- 慢性鼻炎 (CR) 显著影响生活质量,明显的细鼻 (CTR) 是一个常见的症状.
- 后鼻神经 (PNN) 结冰是CR的一种成熟治疗方法,在70-80%的病例中提供症状缓解.
研究的目的:
- 为了评估PNN冷化后CTR复发的时间和程度.
- 评估患者报告的结果和治疗偏好在复发后.
主要方法:
- 一个多中心的回顾性队列研究的CR患者与CTR耐火的ipratropium化鼻喷雾 (IBNS).
- 在中部肉质后侧壁上进行PNN冷.
- 随访至少12个月或直到CTR复发,评估鼻分数 (利克尔特尺度0-5).
主要成果:
- 74名CR患者中的84% (平均年龄58岁,53%的女性,74%的非过敏患者) 在PNN冷后最初有所改善.
- 在有足够的随访 (平均31.6个月) 的60名患者中,95%的患者在平均5个月后出现了CTR复发.
- 65%的复发患者完全恢复了手术前症状;90%的患者需要进一步治疗.
结论:
- PNN冷化可为CR相关的CTR提供显著的初始改善.
- 烦人的CTR的复发很常见,在大多数患者中,治疗后大约5个月发生.
- 高复发率表明需要长期管理策略的CR患者治疗PNN冷.
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