在阻塞性睡眠呼吸暂停的安全性和有效性:系统性审查和分析
Angelica Walker1, Mohamed F Kassir1, Vineeth Sama1
1Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
概括
上前进手术显著改善了阻塞性睡眠呼吸暂停指标,大多数副作用,如面部麻木是暂时的. 这种手术方法为睡眠呼吸暂停治疗提供了最高的成功率.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 睡眠医学 睡眠医学
- 口腔和牙面部外科手术
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是一种普遍的疾病,影响着全世界数以百万计的人.
- 外科干预越来越多地被探索为OSA管理.
- 上下 (MMA) 手术是OSA的公认治疗选择.
研究的目的:
- 进行对MMA手术对OSA的临床有效性的最新评估.
- 分析与MMA手术相关的后果的发生率和性质.
- 为提供MMA手术在OSA患者的结果的全面概述.
主要方法:
- 一项系统性审查和对报告MMA手术对OSA进行研究的元分析.
- 搜索的数据库包括PubMed,Scopus和CINAHL.
- 对比例和平均值的元分析使用随机和固定效应模型进行.
主要成果:
- 在MMA手术中,呼吸障碍指数 (RDI),呼吸障碍指数 (RDI),SPO2 Nadir,Epworth睡眠度量表 (ESS) 和体重指数 (BMI) 显著改善.
- 最常见的后果是早期和晚期下面麻木 (分别为83.40%和66.51%) 和硬件移除 (21.99%).
- 没有报告重大并发症或死亡率;大多数后果是暂时的.
结论:
- 在治疗OSA方面,MMA手术非常有效,在外科选择中,它提供了最高的成功率.
- 过渡性下面麻木是常见的后果,需要进行彻底的手术前咨询.
- 未来的研究应该专注于尽量减少MMA手术后面部下部麻木的风险.
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