相关实验视频
Updated: Jun 3, 2025

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A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
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在巴西,急性肺栓塞住院患者出血
Leonardo Jordan Hansen Vizzotto1, Corina Dos Reis Sepeda1, Carlos Henrique Miranda1
1Division of Emergency Medicine, Department of Internal Medicine, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (FMRP-USP), Ribeirão Preto, SP, Brazil.
Clinics (Sao Paulo, Brazil)
|January 7, 2025
概括
巴西的急性肺栓塞 (APE) 患者经历高出血率. 大型出血显著增加了一年死亡率,目前的预测得分缺乏确定高风险个体的准确性.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 内部医学 内部医学
背景情况:
- 全球急性肺栓塞 (APE) 的发生率正在上升.
- 抗血栓治疗是APE的标准,但存在出血风险.
- 了解巴西APE患者的出血患病率和影响至关重要.
研究的目的:
- 为了确定巴西APE患者的出血患病率.
- 评估出血对死亡率的影响.
- 在这个人群中评估出血预测得分的表现.
主要方法:
- 对159名住院的APE患者进行了回顾性队列研究 (2009年1月至2017年8月).
- 根据TIMI标准分类出血.
- 应用了五个预测得分 (RIETE,PE-SARD,VTE-BLEED,Kuijer,ATRIA) 的结果.
- 评估了30天和一年的死亡率.
主要成果:
- 整体出血发生率为23% (36/159).
- 严重出血 (6%) 与一年死亡率的增加有关 (RR 2.00,p=0.044).
- 所有评估的出血预测得分都显示出低准确度.
结论:
- 巴西APE患者的出血率很高.
- 严重出血是一年死亡率的重要预测因素.
- 目前的出血预测得分对于APE患者在这种情况下是不可靠的.
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