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Updated: Jun 3, 2025

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在急性炎症下,IFNα信号驱动着造血干细胞功能障碍

Xue Han1, Minyi Zhao2, Kexin Wang1

  • 1Department of Hematology, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, Guangdong, China.

International immunopharmacology
|January 7, 2025
PubMed
概括

脂聚糖 (LPS) 通过触发干扰素-α (IFNα) 途径来激活造血干细胞 (HSC),从而导致HSC的激活和耗尽. 肌酸可以逆转这种损伤,保护高细胞免受LPS诱导的损伤.

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