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滴基酸酶4是猪流行性腹病毒感染的辅因子

Yanjie Huang1, Jiayun Wu2, Xueli Zhang1

  • 1College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China.

Veterinary microbiology
|January 7, 2025
PubMed
概括

二乙酶4 (DPP4) 促进了猪流行性腹病毒 (PEDV) 在猪中的感染. 抑制或去除DPP4显著减少PEDV的入侵和复制,确定DPP4作为一个关键的辅助因子.

关键词:
辅助因子 辅助因子 辅助因子双基酸酶 4 (((DPP4) 的二基酸酶.猪流行性腹病毒 (PEDV)

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Dipeptidyl peptidase 4 (DPP-4) is a serine protease widely distributed in the body. It's involved in the inactivation of GLP-1 and GIP hormones, which are crucial for insulin regulation. DPP-4 inhibitors, such as sitagliptin (Januvia), saxagliptin (Onglyza), linagliptin (Tradjenta), alogliptin (Nesina), and vildagliptin (Galvus), help increase the proportion of active GLP-1, enhancing insulin secretion. These inhibitors work by competitively binding to DPP-4. This binding causes a...
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