在沙特阿拉伯人口中血缘关系和听力损失的流行率
Shawq Fayez Aljabri1, Shawg Saleh Alrumaih1, Yousef M Al Mashhrawi2
1Medical Student in Medicine and Surgery, College of Medicine, Imam Muhammed Ibn Saud University, Saudi Arabia.
International journal of pediatric otorhinolaryngology
|January 7, 2025
概括
沙特阿拉伯的血缘关系与儿童听力损失 (CHL) 的更高患病率有关. 这一系统性审查强调了血缘关系与沙特人口遗传性听力损失风险增加之间的重要关联.
科学领域:
- 遗传学 是一个遗传学.
- 公共卫生 公共卫生
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 儿童听力损失 (CHL) 的原因多种多样,沙特阿拉伯被怀疑患病率很高.
- 血缘关系是该地区遗传性听力损失的一个重要因素.
研究的目的:
- 为了确定沙特人口中遗传性听力损失的患病率.
- 确定与遗传性听力损失相关的风险因素,特别是血缘关系.
主要方法:
- 在2023年9月进行了一次系统的文献审查.
- 在PubMed,CENTRAL,MEDLINE和EMBASE数据库中进行了搜索.
- 数据被两个研究人员独立审查.
主要成果:
- 确定了9项研究,显示血缘关系的患病率从21.1%到80.8%.
- 来自血缘关系婚姻的后代表现出持续更高的CHL患病率.
- 据报道,来自血缘关系婚姻的后代患CHL的风险高3.5倍.
结论:
- 在沙特阿拉伯,血缘关系和先天性神经感官听力损失之间存在着强烈的联系.
- 需要有针对性的公共卫生干预措施,包括遗传咨询和婚前查.
- 对沙特人口来说,解决血缘关系对听力健康的影响至关重要.
更多相关视频
09:15Cryosectioning and Immunostaining Mouse Inner Ear Tissue: From Embryonic to Adult Stages
Published on: April 11, 2025
364
00:06Simple Surgical Induction of Conductive Hearing Loss with Verification Using Otoscope Visualization and Behavioral Clap Startle Response in Rat
Published on: October 26, 2019
7.6K
相关概念视频
Hearing
51.8K
When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
51.8K
Prevalence and Incidence
342
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
342
Genome-wide Association Studies-GWAS
12.4K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
12.4K
Incomplete Dominance
21.3K
Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
21.3K
Assessing Blood pressure using a doppler ultrasound
1.2K
To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
1.2K
Heritability
189
Heritability is a statistical concept that measures the degree to which genetic differences among individuals contribute to trait variations within a population. It is a fundamental idea in genetics, often prone to misinterpretation. Heritability is expressed as a percentage, reflecting the proportion of variation in a specific trait across a population that can be linked to genetic differences. However, it's important to understand that heritability does not determine how "genetic"...
189
