间歇性口腔食管养脑小血管疾病患者的消化不良:一项随机对照研究
Hongji Zeng1, Jiaying Yang2, Weijia Zhao3
1School of Public Health, Zhengzhou University, Zhengzhou, China; Dysphagia Research Institute, Zhengzhou University, Zhengzhou, China.
Nutrition (Burbank, Los Angeles County, Calif.)
|January 7, 2025
概括
间歇性耳食管养 (IOE) 改善了脑小血管疾病患者的消化不良和营养状况,比鼻胃管养 (NGT) 更有效. 此外,IOE还减少了吸气性肺炎,改善了日常生活和生活质量.
科学领域:
- 神经学 神经学
- 胃肠病学 胃肠病学
- 临床营养学 临床营养学
背景情况:
- 大脑小血管疾病 (CSVD) 经常导致食不通,影响营养状况和生活质量.
- 鼻管养 (NGT) 是一种常见的干预措施,但其在CSVD患者的疗效需要进一步调查.
- 间歇性耳食管养 (IOE) 为患有吞困难的患者提供了替代的养方法.
研究的目的:
- 为了比较间歇性耳食管养 (IOE) 与鼻胃管养 (NGT) 的临床有效性,在患有CSVD和消化不良的患者中.
- 评估IOE和NGT对失消症严重程度,营养状况,吸气性肺炎发病率,日常生活活动 (ADL) 和生活质量 (QOL) 的影响.
主要方法:
- 一项随机对照性研究涉及60名CSVD患者进行了15天.
- 参与者被分配到IOE组 (n=30) 或NGT组 (n=30).
- 主要结局包括食障碍评估 (透吸收量表,功能性口服摄入量表),次要结局评估营养状况,吸收性肺炎,ADL和QOL.
主要成果:
- 无论是IOE还是NGT组,在治疗后,食障碍,营养状况,ADL和QOL均显著改善.
- 与NGT组相比,IOE组在消化不良,营养状况 (BMI,白蛋白,血红蛋白),ADL和QOL方面表现明显好.
- 与NGT组 (33.33%) 相比,IOE组的吸入性肺炎发生率明显较低 (6.67%).
结论:
- 间歇性耳食管养 (IOE) 比鼻胃管养 (NGT) 更有利于改善CSVD患者的食障碍.
- IOE显著提高了营养状况,日常生活活动和生活质量,同时减少了这种患者群体的吸入性肺炎.
- 这些发现支持IOE作为CSVD患者经历食障碍的优越食策略.
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