抗生素耐药性基因在矿业影响的农田环境中的流行率
Hai-Yan Zou1, Fang-Zhou Gao1, Liang-Ying He1
1SCNU Environmental Research Institute, Guangdong Provincial Key Laboratory of Chemical Pollution and Environmental Safety & MOE Key Laboratory of Environmental Theoretical Chemistry, South China Normal University, Guangzhou 510006, China; School of Environment, South China Normal University, Guangzhou 510006, China.
Ecotoxicology and environmental safety
|January 7, 2025
概括
矿业用重金属污染了农田,增加了土壤和作物中的抗生素耐药性基因 (ARG). 这项研究将金属污染与特定的ARG联系起来,并确定潜在的微生物宿主,强调环境风险.
科学领域:
- 环境科学 环境科学
- 微生物学 微生物学
- 环境化学环境化学
背景情况:
- 采矿在土壤和作物中产生重金属污染.
- 重金属可以通过共同选择驱动抗生素耐药性.
- 矿业受影响地区的抗生素耐药性基因 (ARG) 概况尚不清楚.
研究的目的:
- 调查矿业影响的农田土壤和蔬菜中的重金属污染和ARG概况.
- 探索重金属,ARG,移动遗传元素和微生物群落之间的相关性.
- 为了比较一个受矿业影响的村庄 (SB) 和一个参考村庄 (TP) 的这些因素.
主要方法:
- 从受采矿影响的村庄和参考村庄收集了土壤和蔬菜样本.
- 量化了重金属度,ARG丰度和移动遗传元素.
- 微生物社区的组成是使用测序来分析的.
- 进行了统计分析,包括斯皮尔曼的相关性和网络分析.
主要成果:
- 受采矿影响的矿场显示大多数重金属 (Cr除外) 的含量高于中国标准.
- 在受采矿影响的土壤和蔬菜中发现了更高的ARG丰度,特别是对硫胺,氨基醇和四环素耐药基因.
- 这些ARG与重金属度 (Cu,Pb,Zn) 之间观察到正相关性.
- 来自蛋白质细菌和活性细菌的特定微生物系与ARG有关,这表明潜在的宿主.
结论:
- 采矿活动严重污染了农田的重金属.
- 这种污染对共同选择产生了压力,促进了ARG在环境中的持久性.
- 了解这些关系对于管理与采矿相关的环境风险至关重要.
相关概念视频
00:57Antibiotic Selection
52.2K
Overview
52.2K
01:33Bacterial Transformation
55.1K
In 1928, bacteriologist Frederick Griffith worked on a vaccine for pneumonia, which is caused by Streptococcus pneumoniae bacteria. Griffith studied two pneumonia strains in mice: one pathogenic and one non-pathogenic. Only the pathogenic strain killed host mice.
Griffith made an unexpected discovery when he killed the pathogenic strain and mixed its remains with the live, non-pathogenic strain. Not only did the mixture kill host mice, but it also contained living pathogenic bacteria that...
Griffith made an unexpected discovery when he killed the pathogenic strain and mixed its remains with the live, non-pathogenic strain. Not only did the mixture kill host mice, but it also contained living pathogenic bacteria that...
55.1K
00:46Genomic DNA in Prokaryotes
43.4K
The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...
Genomic Diversity in Bacteria
Although bacterial genomes are much...
43.4K