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揭示电子烟补充液中的和多基物质污染:全面的分析评估

Paweł Kubica¹, Tomasz Majchrzak¹, Christina Vakh²

¹Department of Analytical Chemistry, Faculty of Chemistry, Gdańsk University of Technology (GUT), ul. G. Narutowicza 11/12, 80-233 Gdańsk, Poland.

The Science of the total environment

|January 7, 2025

概括

在84%的电子烟液体中检测到和多基物质 (PFAS). 发现了高水平的特定PFAS,引发了对电子烟暴露的健康和环境问题.

科学领域:

环境化学环境化学
分析化学分析化学
毒理学毒理学毒理学

背景情况:

和多基基物质 (PFAS) 是持久的环境污染物.
电子烟的使用正在增加,这引发了人们对潜在暴露路径的担忧.
电子烟补充液中的PFAS污染可能源于制造,包装或设备部件.

研究的目的:

开发和验证一种可靠的分析方法,用于在电子烟补充液中确定PFAS.
调查商业电子烟补充液中的各种PFAS的存在和度.
评估电子烟中PFAS对健康和环境的潜在影响.

主要方法:

使用弱离子交换吸附剂进行固体相提取 (SPE).
高性能液体染色学-并联质谱法 (HPLC-MS/MS) 用于检测.
实验设计 (DoE) 用于方法优化.

主要成果:

一种经过验证的方法,具有较低的检测极限 (0.241.1 pg/mL) 和良好的重复性 (<17%).
在31个分析的电子烟补充液样本中,PFAS在84%中被检测到.
发现PFNA,PFHxA,PFBS,HFPO-DA (GenX) 和N-EtFOSAA的度较高;PFBS是最常见的 (39%).
在含有20毫克/毫升尼古丁的液体中,与含有6毫克/毫升尼古丁的液体中观察到更高的PFAS水平.

结论:

开发的HPLC-MS/MS方法适合在电子烟液中准确量化PFAS.
电子烟补充液体是PFAS暴露和环境释放的潜在来源.
需要进一步的研究来了解蒸汽制品中PFAS的毒理效应和长期环境影响.

关键词:

电子烟补充液体的使用情况永远的化学品永远的化学品液体色谱学液体色谱学液体色谱学 -和多基基物质 (PFAS) 的使用.固体相提取方法固体相提取方法协奏式质谱测量质谱测量

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