对于食道癌的救援手术:需要更加密集的监测监测
Rand Abdulrahman1, Natallia Kharytaniuk2, Nuha Birido1
1Royal College of Surgeons in Ireland - Medical University of Bahrain, Manama, Bahrain.
对食道癌的密集监测在近12%的患者中检测到新的或复发的疾病,使得救援手术成为可能. 这种方法表明,与标准护理相比,生存结果不差.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
背景情况:
- 目前对食道癌的监测缺乏标准化的协议,通常依赖于可能推迟诊断的症状.
- 这可能会对患者的生存率产生负面影响,因为复发或新出现的原发性瘤的检测延迟了.
研究的目的:
- 评估密集监测策略在检测可治愈的食道癌复发或新的原发性瘤方面的有效性.
- 评估与这种密集监测政策相关的生存结果.
主要方法:
- 分析了针对食道癌治疗患者的前性数据库.
- 监测包括定期诊所检查,内镜与活检 (每3个月至3年,然后每6个月至5年,随后每年一次),以及计算机断层扫描 (CT) 扫描 (每6个月至3年,然后每年一次).
主要成果:
- 在205名患者中,有24名 (11.7%) 通过监测检测出新的或复发的癌症,有资格接受救援手术.
- 在接受救援手术的患者中,中位生存时间为51.8个月,5年生存率为45.8%.
- 这些结果并不低于整体队列 (中位生存时间为30.2个月,5年生存率为32.6%).
结论:
- 密集监测成功确定了近12%的可切除的复发性或第二次原发性食道癌症患者.
- 通过密集监测发现的患者的结果与一般队列相似.
- 需要进一步的研究来优化食道癌的监测计划和方法.
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