在以全移植,异种移植和支架的生物假体门代替大动脉根之后,重新进行干预
Takuya Ogami1, Derek Serna-Gallegos1, Floyd W Thoma2
1Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA, United States of America; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, United States of America.
概括
用非机械门替换大动脉根之后的重新干预并不常见,结构门恶化是主要原因. 在这项研究中,门类型没有影响长期死亡率.
科学领域:
- 心血管外科心血管外科
- 生物材料科学 生物材料科学
- 医疗器械技术 医疗器械技术
背景情况:
- 在主动脉疾病管理中越来越多地使用非机械.
- 在使用非机械假肢进行大动脉根置换 (ARR) 后,对再干预率的数据有限.
- 了解重新干预模式对长期患者结果的重要性.
研究的目的:
- 评估使用非机械门进行大动脉根置换 (ARR) 后再干预的发生率和原因.
- 评估与ARR中使用的不同类型的非机械门相关的长期死亡率.
- 调查跨导管干预在重新干预策略中的使用情况.
主要方法:
- 一个单一中心的回顾性研究,对523名接受ARR的患者进行了整体移植,异种移植或支架生物假体管 (2010-2020年).
- 对主动脉再干预的累积发病率的分析.
- 对长期死亡率预测因素的考克斯危险回归分析.
主要成果:
- 整体再干预率为4.0% (21名患者),再干预的中位时间为4.77年.
- 结构的恶化 (12例) 和传染性内心炎 (6例) 是重新干预的主要原因.
- 没有进行过导管重复干预;预期的10年重复干预率为8.1%.
- 排泄分数<30%和心力衰竭与死亡率有关,但门类型没有.
结论:
- 在ARR后对非机械进行大动脉的重新干预并不常见.
- 在这个队列中,透管入干预不是常见的策略.
- 使用的非机械的类型没有影响长期死亡率.
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