探索免疫能力,HPA轴功能和断奶前乳牛小牛的表现之间的关系
Alessio Cotticelli1, Giovanna Bifulco1, Matilde Giombolini2
1Department of Veterinary Medicine and Animal Production, Federico II University, 80137 Naples, Italy.
Animals : an open access journal from MDPI
|January 8, 2025
概括
管理实践影响奶牛小牛的生长和健康. 疾病发生和个人住房对体重和每日体重增加产生负面影响,突显了压力,免疫力和表现之间的联系.
科学领域:
- 动物科学动物科学
- 兽医医学 兽医医学 兽医医学
- 内分泌学 在内分泌学.
背景情况:
- 皮质醇和DHEA是压力和性的关键指标.
- 这些激素可以与免疫能力一起整合到性能指标中.
- 了解下丘脑-垂体-上腺 (HPA) 轴对于小牛的健康至关重要.
研究的目的:
- 调查管理对乳牛生长的转移效应.
- 探索HPA轴,免疫能力和预先断奶小牛的表现之间的关系.
- 评估早期生活经验对小牛发育的影响.
主要方法:
- 一个综合的回顾性和前性队列研究设计.
- 测量生长性能,疾病发生,头发类固醇 (皮质醇,DHEA,S) 和免疫球蛋白G (IgG).
- 管理因素,荷尔蒙特征和绩效指标之间的相关性分析.
主要成果:
- 断奶前的疾病和长时间的个人住房与60天后的体重有负相关性.
- 头发皮质醇与DHEA的比例在T2显示了与每日体重增加,血IgG和明显的吸收效率的负相关性.
- 静态负荷对免疫能力产生负面影响,而弹性与增长的改善有关.
结论:
- 管理实践,特别是疾病发病率和住房持续时间,显著影响小牛的生长.
- HPA轴,免疫能力和生长性能在预先断奶的乳牛中相互联系.
- 早期生活压力和弹性标记对于优化小牛的发育和表现至关重要.
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