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基于硫醇的氧化还原分子:对烯胺毒性的潜在解剂

Valeria Martin1, Michael Trus1, Daphne Atlas1

  • 1Department of Biological Chemistry, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.

Antioxidants (Basel, Switzerland)
|January 8, 2025
PubMed
概括

烯胺 (ACR) 暴露会引起氧化应激,并激活基激活蛋白激酶 (MAPKs). 基于醇的分子,特别是含有更多氨酸残留的氨酸模拟 (TXM) ,有效抑制了ACR诱导的MAPK激活,并显示出作为抗毒剂的希望.

关键词:
在AD4/NACA中使用.灭症 (apoptosis) 是一种死亡的过程.氧化应激是一种氧化应激.铁素还原酶是一种 thioredoxin.毒性的毒性 毒性的毒性

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