聚烯衍生微生物群代谢物和心血管健康:人体研究的简要回顾
Ana Clara da C Pinaffi-Langley1,2, Stefano Tarantini1,3,4,5,6, Norman G Hord7
1Oklahoma Center for Geroscience and Healthy Brain Aging, University of Oklahoma Health Sciences, Oklahoma City, OK 73117, USA.
Antioxidants (Basel, Switzerland)
|January 8, 2025
概括
饮食中的多,如异黄和基,与肠道微生物群相互作用,影响心血管健康. 了解这种复杂的关系是个性化营养策略的关键,以改善健康结果.
科学领域:
- 植物生物学和人类健康
- 营养科学和微生物学.
背景情况:
- 聚是具有健康益处的植物化合物,特别是对心脏代谢健康有益.
- 由于可变的生物可用性和代谢,多的作用机制尚不清楚.
- 肠道微生物群在多代谢和健康影响中发挥着关键作用.
研究的目的:
- 审查多-肠道微生物群相互作用的最新进展.
- 专注于异黄和基以及它们对心血管健康的影响.
- 确定精准营养的研究缺口.
主要方法:
- 人类观测研究的综述 (过去10年).
- 对多和微生物代谢物进行干预研究的分析.
- 专注于特定的多类 (异黄,胺) 和它们的元类型.
主要成果:
- 观察性研究将异黄,基和它们的代谢类型与改善的心血管风险因素联系起来.
- 干预性研究揭示了一个复杂的,尚未完全理解的多-肠道微生物群相互作用.
- 有证据表明,影响健康结果的双向关系.
结论:
- 多-肠道微生物群轴对心血管健康至关重要.
- 针对这一轴的个性化营养策略有望改善健康.
- 需要进一步的研究来阐明机制和优化干预措施.
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