体重指数和脏瘤侧向化之间的相关性:对生存和风险因素的洞察
Mateusz Czajkowski1, Michał Falis2, Anton Żawrocki3
1Department of Urology, Medical University of Gdańsk, 80-214 Gdańsk, Poland.
Cancers
|January 8, 2025
概括
超重个体的右侧瘤发病率较高,但瘤横向化没有影响细胞癌 (RCC) 患者的存活率. 需要进一步的研究来理解这种关联.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 癌,特别是细胞癌 (RCC),是全球重要的健康问题,约占癌症诊断和死亡人数的2%.
- 虽然已确立的RCC风险因素包括年龄,性别,吸烟,高血压和体重状况,但这些因素与瘤横向化之间的关系仍未得到充分研究.
研究的目的:
- 这项研究旨在调查RCC手术治疗的患者体质指数 (BMI) 和瘤侧向化之间的关联.
- 此外,研究还试图确定瘤横向化对整体存活率 (OS) 和癌症特异性存活率 (CSS) 的影响.
主要方法:
- 一项单一中心研究涉及287名患者,他们在2016年1月至2019年12月期间接受了脏瘤手术治疗.
- 根据BMI,患者被分为正常,超重或肥胖的组. 收集的数据包括人口统计,组织病理学以及吸烟和高血压等危险因素.
主要成果:
- 右侧瘤的患病率比左侧瘤 (44.95%) 高 (55.05%).
- 在较高的BMI (超重类别) 和右侧瘤的频率增加之间发现了显著的相关性 (p=0.04731).
- 在正常或肥胖群体中,瘤横向化和BMI之间没有观察到任何关联,也没有与吸烟或高血压有关. 在右侧和左侧瘤之间,生存率没有显著差异.
结论:
- 这项研究表明,在被研究的队列中,超重患者中,右侧瘤的发生率较高.
- 瘤侧向化在癌中没有发现与总体或癌症特异性生存率的显著差异有关.
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