对原发性病和相关精神病并发症的治疗方法
Irene Berzosa-Gonzalez1,2,3,4, Saul Martinez-Horta1,2,3,4, Jesus Pérez-Pérez1,2,3,4
1Movement Disorder Unit, Neurology Department, Hospital de Sant Pau, 08041 Barcelona, Spain.
Brain sciences
|January 8, 2025
概括
阿里皮普拉和克罗纳泽帕姆在提克障碍和并发症方面显示出有利的结果. 克罗纳泽帕姆可能是一个有用的第一线或辅助疗法,为选定的患者.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 症严重影响幸福感和人际关系.
- 对于提克障碍和并发性疾病的最佳药理疗法 (PT) 尚不清楚.
- 这项研究描述了一组患有滴答障碍的患者的临床特征和治疗方法.
研究的目的:
- 描述患有动障碍的患者的临床特征和动和精神伴随性疾病的治疗方法.
- 量化的严重程度,并发症负担和整体严重程度.
- 在随访期间评估临床变化.
主要方法:
- 在功能单位对患者进行回顾性描述性研究 (2022年1月 - 2024年3月).
- 两位神经科医生应用了临床全球变化印象 (CGI-C) 和严重程度 (CGI-S) 尺度.
- 分析了基线和最后评估数据.
主要成果:
- 包括36名患者:94.4%患有图雷特综合征 (TS).
- 86%的人患有精神伴随性疾病:OCS (52%),焦虑 (52%),多动症 (35%).
- 阿里皮普拉和克罗纳泽帕姆是最常用于;SSRI和二西平用于并发症. 轻微的整体改善 (CGI-C3),儿童/青少年的改善更大 (CGI-C2).
结论:
- 阿里皮普拉和克罗纳泽帕姆在提克障碍和并发症方面表现出良好的临床结果.
- 这些药物似乎比其他治疗方法更有效.
- 克洛纳泽帕姆可以作为一线单一疗法或辅助治疗在特定情况下的滴答和并发症.
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