抑郁症,焦虑症和神经精神疾病症状负担在长度队列中,患有持续的心理物理后COVID嗅觉功能障碍
Tiana M Saak1, Jeremy P Tervo1, Brandon J Vilarello2
1Vagelos College of Physicans and Surgeons, Columbia University, New York, NY 10032, USA.
Brain sciences
|January 8, 2025
概括
在COVID-19之后持续的嗅觉功能障碍与持续的抑郁和焦虑有关. 在最初感染后很长一段时间内,神经心理症状,如难以找到单词的困难仍然很常见.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 传染病流行病学 传染病流行病学
背景情况:
- 嗅觉功能障碍 (OD) 是一种常见的神经症状,影响生活质量.
- 持续的COVID-19相关的嗅觉功能障碍 (C19OD) 可能会加剧神经精神病的后果.
- 了解C19OD对心理健康的长期影响至关重要.
研究的目的:
- 在C19OD患者中描述抑郁,焦虑和神经精神症状的纵向负担.
- 评估这些症状随着时间的推移而持续的程度.
- 为了告知长期COVID患者的临床管理和支持.
主要方法:
- 未来的纵向研究,包括具有验证心理物理C19OD的个体.
- 使用嗅探棒进行嗅觉评估.
- 在基线和一年后的随访中使用PHQ-9,贝克焦虑清单和神经精神病症状问卷.
主要成果:
- 找字和注意力困难是最常见的神经精神病症状.
- 在基线时41%的人报告抑郁症,在随访时38%.
- 在基线时报告的焦虑率为29%,在随访时为27%.
结论:
- 患有C19OD的个体面临着持续性神经精神疾病的显著风险.
- 这些神经和精神症状在纵向评估中仍然明显.
- 与C19OD相关的后果可能在COVID-19诊断后持续数年.
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