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使用纳米孔序列的分子鉴定Dibothriocephalus nihonkaiense感染:一个案例报告和文献评论

Hin-Fung Tsang¹, Stanley W M Leung¹, Tin-Nok Hung¹

¹Department of Clinical Laboratory and Pathology, Hong Kong Adventist Hospital, Hong Kong SAR, China.

Diagnostics (Basel, Switzerland)

|January 8, 2025

概括

在香港出现了一例罕见的Dibothriocephalus nihonkaiense感染病例. 纳米孔测序证实了寄生虫,患者在接受了普拉齐量子特治疗后康复.

科学领域:

医学寄生虫学医学寄生虫学
传染性疾病传染性疾病
基因组学就是基因组学.

背景情况:

在香港,Dibothriocephalus nihonkaiense感染并不常见.
这种由鱼类传播的虫通过含有虫菌的生鱼或未煮熟的鱼感染人类.

研究的目的:

在香港报告D. nihonkaiense感染病例.
为了证明纳米孔测序对寄生虫识别的有用性.

主要方法:

临床病例呈现与腹部X射线.
使用纳米孔测序对寄生虫进行鉴定.
实验室检测包括完整血清和维生素B12水平.

主要成果:

在患者的便中发现了一个80厘米长的带和D. nihonkaiense的特征蛋.
在周围血液中发现单细胞百分比升高.
用普拉齐素成功治疗,没有复发.

结论:

这一病例突显了香港罕见的D. nihonkaiense感染.
牛津纳米孔下一代测序 (NGS) 是有效的准确的寄生虫识别.

关键词:

迪波特里奥塞法卢斯 (Dibothriocephalus nihonkaienseenseense) 是一种神经发育不正常的疾病.这种类型的体质是Diphyllobothrium nihonkaienseenseense.这种疾病叫做diphyllobothriasis.胃上部疼痛胃上部疼痛鱼类带状虫是一种这是一个纳米孔.这是下一代测序.

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