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Updated: Jun 3, 2025

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在ApoE缺陷小鼠的动脉样硬化进展过程中生成转录长度变异和mRNA剪接的重编程

Miguel Hueso1,2, Adrián Mallén1, Estanis Navarro3

  • 1Experimental Nephrology Lab, Institut d'Investigació Biomèdica de Bellvitge-IDIBELL, C/Feixa Llarga s/n, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.

Biomedicines
|January 8, 2025
PubMed
概括

在动脉样硬化进展过程中发生mRNA长度变化,包括5'UTR/3'UTR延长和CDS缩短. 拼接重编程和转录异形切换有助于与疾病相关的mRNA多样性.

关键词:
5′UTR/3′UTR延长时间其他替代拼接签名动脉样硬化 动脉样硬化转换的mRNA异形转换.拼接 重编程 重编程

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