电子烟对生理途径的影响和提议使用Bixin进行治疗干预
Sophia Rene Claymore1, Diane S Allen-Gipson1,2
1Department of Pharmaceutical Sciences, USF Health Taneja College of Pharmacy, University of South Florida, Tampa, FL 33612, USA.
Biomedicines
|January 8, 2025
概括
电子烟 (e-cigs) 会导致细胞损伤和炎症. 比克辛纳米颗粒由于其抗炎和抗氧化特性,对治疗电子烟引起的伤害有前途.
科学领域:
- 毒理学 毒理学 毒理学
- 纳米医学是一种纳米医学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 电子烟 (e-cigs) 的普及率激增,引发了人们对其长期健康影响的担忧.
- 电子烟通过蒸发提供尼古丁和化学物质,研究表明它对细胞具有细胞毒性作用和炎症途径失调.
- 最初作为吸烟的更健康的替代品销售,电子烟对肺部,心血管和脑血管健康构成风险.
研究的目的:
- 审查电子烟使用对健康的有害影响.
- 探索比克辛的治疗潜力,Bixa orellana的阿波卡罗类,以减轻电子烟引起的伤害.
- 研究纳米技术在提供潜在治疗药物中的应用.
主要方法:
- 关于电子烟对健康的影响研究的文献综述.
- 对比克辛的抗炎,抗氧化和抗癌功能的研究进行了审查.
- 分析纳米技术在药物输送中的应用,用于治疗有毒暴露.
主要成果:
- 电子烟使用与上皮细胞和内皮细胞中细胞毒性有关.
- 比克辛表现出显著的抗炎和抗氧化活性.
- 比克辛的纳米粒子配方提供了针对性交付和增强疗效的潜在优势.
结论:
- 电子烟对人类健康构成重大风险,影响多个器官系统.
- 比克辛,特别是纳米粒子形式,为抵消电子烟诱导的细胞损伤和炎症提供了一个有前途的治疗策略.
- 对基于bixin的纳米医学进行进一步的研究可能会导致用于vaping相关健康问题的新治疗方法.
更多相关视频
09:30A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol
Published on: January 18, 2018
8.3K
10:44Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
11.4K
相关概念视频
01:29Stimulants
158
Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
158
01:23Drugs Acting on Autonomic Ganglia: Stimulants
1.3K
Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating...
1.3K
01:27CNS Depressants: Alcohol and Nicotine
170
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
170