在患有双动脉的儿科患者左心室功能障碍的斑点应变分析-A试点研究
Amalia Făgărășan1,2, Simina-Elena Ghiragosian-Rusu1,2, Claudiu Ghiragosian3
1Department of Pediatrics III, Faculty of Medicine, George Emil Palade Univ Med Pharm Sci&Technol. of Târgu Mureș, 540142 Târgu Mureș, Romania.
Children (Basel, Switzerland)
|January 8, 2025
概括
双主动脉 (BAV) 在儿童中显示出正常的射出分数,但左心室全球纵向应变 (LV GLS) 减少,特别是在特定的段落. 需要进一步的研究来将其与心力衰竭联系起来,并改善早期检测.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 遗传性心脏病是一种先天性心脏病.
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 双动脉 (BAV) 是儿童常见的一种先天性心脏缺陷.
- 评估左心室 (LV) 缩功能对于管理儿科BAV至关重要.
- 左心室全球纵向应变 (LV GLS) 是心肌变形的敏感指标.
研究的目的:
- 为了分析儿科BAV患者的缩功能,使用LV喷射分数 (EF) 和LV GLS.
- 为了比较BAV患者和对照组之间的LV缩功能.
- 使用斑点跟踪回声心脏图 (STE) 调查细分LV功能.
主要方法:
- 对6至17岁的患有BAV的儿童和对照组进行前性研究.
- 使用经典的LV EF测量和STE进行LV GLS分析.
- 在2023年1月至2024年1月期间收集的数据.
主要成果:
- 研究了BAV组 (73名患者) 和对照组 (55名患者).
- 在角四腔视图中,BAV患者表现出正常的LV EF,但显著减少LV GLS (p=0.022).
- 在BAV患者的下部和前部部分观察到减少的应变.
结论:
- 儿科BAV患者可能有亚临床心肌功能障碍,尽管正常EF.
- 在BAV中减少的LV GLS需要进一步调查临床心力衰竭的发展.
- 早期发现减少的LV GLS可能会降低发病率.
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