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小鼠对BCG疫苗接种的细胞和转录基因早期先天性免疫反应

Liya G Kondratyeva1,2, Olga A Rakitina1, Victor V Pleshkan1,2

  • 1Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow 117997, Russia.

Cells
|January 8, 2025
PubMed
概括

巴西尔·卡尔梅特-盖林 (BCG) 疫苗可以增强小鼠的先天免疫细胞,增加脏和骨髓中的单细胞和NK细胞. 这种早期反应显示了转录基因变化,可能会增强训练免疫力 (TRIM).

关键词:
在BCG中,BCG是BCG.在RNA-seqqq.这是先天免疫力.训练有素的免疫力转录组 (transcriptome) 是一个转录组.接种疫苗 接种疫苗

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