在子宫内膜异位症的nociplastic疼痛:一个范围审查
Avonae Gentles1,2, Emma Goodwin2, Yomna Bedaiwy2
1Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC V6H 3N1, Canada.
Journal of clinical medicine
|January 8, 2025
概括
本综述探讨了在子宫内膜异位症患者中识别脑内膜异位症疼痛和中心敏感化 (CS) 的工具. 目前的方法各不相同,这凸显了对标准化评估的需要,以改善这种慢性疼痛疾病的诊断和治疗.
科学领域:
- 疼痛医学 医学 疼痛医学
- 妇科 妇科 妇科 妇科
- 神经学 神经学
背景情况:
- 子宫内膜异位症是一种炎症性疾病,会引起复杂的疼痛,包括脑膜异位症疼痛.
- 中枢敏感性 (CS) 是脑膜疼痛的一个关键机制,但缺乏标准化的检测方法.
- 精确识别CS/nociplastic疼痛对于有效的子宫内膜异位症疼痛管理至关重要.
研究的目的:
- 审查和识别可用的评估工具,以表征子宫内膜异位症中中央敏感性 (CS) 和脑膜异位症疼痛.
- 了解与子宫内膜异位症相关的慢性盆腔疼痛中这些疼痛机制的诊断方法的当前情况.
主要方法:
- 在主要数据库 (MEDLINE,Embase,Scopus,PsychINFO) 中使用PRISMA-P协议进行系统的文献搜索.
- 关键词包括"子宫内膜异位症"",中央敏感化"",鼻膜疼痛"",广泛疼痛"和"评估工具".
- 包括提到在子宫内膜异位症患者中检测鼻膜性疼痛或CS的工具的研究.
主要成果:
- 30篇论文满足了从379个引用中包含的标准.
- 评估工具包括患者报告的问卷 (14项研究),定量感官测试 (QST) (6项研究),临床评估 (2项研究) 和综合方法 (8项研究).
- 在用于识别子宫内膜异位症和子宫内膜异位症疼痛的工具中存在显著的多样性.
结论:
- 目前用于识别子宫内膜异位症中中央敏感性和nociplastic疼痛的方法是多样化的.
- 进一步的研究对于验证这些工具和标准化方法是必不可少的.
- 标准化将提高诺西普拉斯疼痛识别的准确性,并指导子宫内膜异位症患者的向治疗策略.
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