对刺激性肠综合征的饮食干预的有效性:系统性审查和网络元分析
Hossein Haghbin1, Fariha Hasan2, Manesh Kumar Gangwani3
1Division of Gastroenterology and Hepatology, Bon Secours Mercy Health, Toledo, OH 43608, USA.
Journal of clinical medicine
|January 8, 2025
概括
低FODMAP饮食和地中海饮食有效地改善了刺激性肠综合征 (IBS) 的症状和生活质量. 需要进行进一步的对比试验,特别是地中海饮食,以确认其在治疗IBS方面的优越性.
科学领域:
- 胃肠病学 胃肠病学
- 营养科学 营养科学
- 临床研究 临床研究
背景情况:
- 刺激性肠综合征 (IBS) 显著影响患者的生活质量.
- 饮食干预对于控制IBS症状至关重要.
- 低FODMAP饮食 (LFD),无质饮食 (GFD) 和地中海饮食被认为具有潜在的有效性.
研究的目的:
- 进行一个网络元分析,比较LFD,GFD和地中海饮食的IBS.
- 确定改善IBS结果的最有效的饮食干预措施.
- 评估这些饮食对IBS生活质量和症状严重性的影响.
主要方法:
- 随机对照试验 (RCT) 的系统综述公布至2024年3月14日.
- 包括来自Embase,PubMed,MEDLINE OVID,Web of Science,CINAHL Plus和Cochrane Central的研究. 这些研究包括在内.
- 应用随机效应模型用于使用频率主义方法的直接和网络元分析.
主要成果:
- 与标准饮食相比,低FODMAP饮食 (LFD) 在IBS症状严重程度尺度 (IBS-SSS) 和IBS生活质量 (IBS QOL) 上显示出统计学上显著的改善.
- 对于任何IBS评分,无质饮食 (GFD) 和LFD或标准饮食之间没有发现显著差异.
- 地中海饮食在IBS-SSS,IBS-QOL,膨胀,不满和一般生活干扰方面的改善排名最高.
结论:
- 饮食干预措施,特别是LFD和地中海饮食,有效缓解IBS症状并提高生活质量.
- 地中海饮食似乎为IBS管理提供了最全面的好处.
- 建议进行进一步的大规模RCT与直接比较,以巩固这些发现,特别是地中海饮食.
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