2型糖尿病患者尿路感染的预测因素
Teodora Sorescu1,2,3, Andrei Cosnita4, Adina Braha1,2,3
1Second Department of Internal Medicine: Diabetes, Nutrition, Metabolic Diseases, and Systemic Rheumatology, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Journal of clinical medicine
|January 8, 2025
概括
尿路感染 (UTI) 在2型糖尿病 (T2D) 患者中很常见. 长期的疾病,血糖控制不良和糖尿病并发症显著增加T2D个体的尿路感染风险.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
背景情况:
- 糖尿病患者面临感染的风险增加.
- 尿路感染 (UTI) 在2型糖尿病 (T2D) 患者中尤为普遍.
研究的目的:
- 确定在罗马尼亚蒂米索拉住院的T2D患者中尿道感染的患病率.
- 在这个患者队列中确定与尿路感染相关的关键风险因素.
主要方法:
- 对1139名接受尿液培养的成年T2D住院患者的医院记录进行了回顾性审查.
- 对人口统计数据,临床特征和实验室结果的分析.
主要成果:
- 尿路感染的总体患病率为19.7%,女性 (27.5%) 的患病率明显高于男性 (9.8%).
- 增加的尿路感染风险与年龄较大,DM持续时间较长,BMI较高,HbA1c升高以及DM相关并发症如视网膜病,慢性病,多神经病和脑血管疾病的存在有关.
- 使用-葡萄糖共载体2 (SGLT2) 抑制剂并没有影响尿路感染风险.
结论:
- 患有延长疾病持续时间,低于最佳血糖控制和现有的糖尿病并发症的T2D患者患尿路感染的风险更大.
- 开发有针对性的治疗策略以减轻这些已识别的风险因素对于管理T2D患者的尿路感染至关重要.
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