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目前基于非病毒的策略来制造CAR-T细胞

Leon Gehrke1, Vasco Dos Reis Gonçalves1, Dominik Andrae1

  • 1Medizinische Klinik und Poliklinik II und Lehrstuhl für Zelluläre Immuntherapie, Universitätsklinikum Würzburg, 97080 Würzburg, Germany.

International journal of molecular sciences
|January 8, 2025
PubMed
概括

研究人员正在探索用于化学抗原受体T细胞 (CAR-T) 疗法制造的非病毒基因转移方法. 这些替代方案旨在提高安全性,降低成本和提高效率,与传统的病毒载体相比.

关键词:
在CAR-T细胞中.克里斯普尔是什么意思?克里斯普尔是什么意思?基因转移是转移基因的过程.没有整合的非整合.非病毒性非病毒性.猪背包 (Piggybac) 是一个产品.可编程的内核酶.睡梦中的美女这是一个短暂的过渡.转换酶可以转换.

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