释放和分解性质的Poly (乳酸) 薄膜与烯异硫酸酸-β-环极素含有复合体的活性食品包装
Cristina Muñoz-Shugulí1,2, Francisco Rodríguez-Mercado2, Abel Guarda2
1Facultad de Ciencias, Escuela Superior Politécnica de Chimborazo (ESPOCH), Riobamba EC060155, Ecuador.
Molecules (Basel, Switzerland)
|January 8, 2025
概括
研究人员开发了用β-cyclodextrin (β-CD) 和allyl isothiocyanate (AITC) 的活性聚乳酸 (PLA) 薄膜,以提高抗菌性能和更快的堆肥. 这些可持续的薄膜提供了有前途的生物降解包装解决方案.
科学领域:
- 材料科学 材料科学 材料科学
- 聚合物化学 聚合物化学
- 食品包装技术 食品包装技术
背景情况:
- 聚乳酸 (PLA) 是一种可生物降解的聚合物,有可能用于食品包装.
- 提高PLA的特性,如抗微生物活性和可堆肥性,对于更广泛的应用至关重要.
- 酸 (AITC) 具有抗微生物特性,但需要控制释放机制.
研究的目的:
- 为了提高PLA薄膜的功能性质和可堆肥性.
- 为了将AITC的β-cyclodextrin (β-CD) 纳入复合物纳入PLA膜中.
- 评估开发的薄膜的结构,化学,形态,热,屏障和抗菌性质.
主要方法:
- 融挤出用于制备与β-CD:AITC包容复合物相结合的PLA薄膜.
- 描述包括分析结构性,化学性,形态性,热性和屏障性.
- 在不同的湿度条件下评估了AITC的抗菌功能和释放动力学.
- 纯PLA和改性PLA薄膜之间的堆肥分解率进行了比较.
主要成果:
- β-CD:AITC复合物提高了PLA薄膜的热稳定性和吸收湿度.
- AITC的释放依赖于湿度,在低湿度下保持抗菌活性,在高湿度下有效释放.
- 在堆肥条件下,添加5%和10%的β-CD:AITC复合物加速了薄膜分解.
- 经过修改的PLA薄膜在23天内实现了高达90%的分解,与纯PLA相比,将堆肥时间缩短了5天.
结论:
- 含有β-CD:AITC复合物的PLA薄膜具有增强的功能性质.
- 这些材料表现出加速的生物降解,使它们适合可持续包装.
- 开发的片代表了可生物降解的抗微生物食品包装的有希望的解决方案.
相关概念视频
01:05Bioavailability Enhancement: Drug Stability Enhancement and GI Retention
Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...
01:22Modified-Release Drug Delivery Systems: Rate-Programmed I
Rate-programmed drug delivery systems (DDS) are designed to release drugs at specific, controlled rates to maintain consistent therapeutic levels. These systems are categorized based on their release mechanisms, including dissolution-controlled DDS, diffusion-controlled DDS, and combined dissolution-diffusion-controlled DDS.In dissolution-controlled DDS, the release rate depends on the slow dissolution of the drug itself or the surrounding matrix. Drugs with inherently slow dissolution rates,...
01:11Oral Drug Delivery Systems: Delayed-Release Systems
Delayed-release drug delivery systems are specialized pharmaceutical formulations designed to postpone the release of active compounds until the drug reaches a specific region of the gastrointestinal (GI) tract, typically the intestine. These systems are essential for drugs that may cause gastric irritation, are unstable in acidic environments, or need to exert therapeutic effects locally in the intestinal or colonic regions.The core feature of delayed-release systems is the use of enteric...
01:25Production of Organic Acids
Lactic acid, an important organic acid extensively applied in food, pharmaceutical, and biodegradable polymer industries, is primarily produced via microbial fermentation. This method is favored over chemical synthesis due to its environmental sustainability and capacity for enantiomerically pure product formation. Among various microbial processes, the fermentation of starch-based substrates stands out due to the abundance and renewability of raw materials like corn and potatoes.Hydrolysis of...
01:27Bioplastics
Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...