相关实验视频
Updated: Jul 1, 2026

10:33
Generation of Alginate Microspheres for Biomedical Applications
Published on: August 12, 2012
20.7K
油脂凝和益生菌装载酸盐载体的混合系统,可用于化品中的潜在应用
Anna Łętocha1, Małgorzata Miastkowska1, Elżbieta Sikora1
1Cracow University of Technology, Faculty of Chemical Engineering and Technology, 31-155 Cracow, Poland.
Molecules (Basel, Switzerland)
|January 8, 2025
概括
与挤出相比,乳化技术提高了油脂凝中的益生菌生存率. 结干燥的含有 Lactobacillus casei (L. casei) 的酸盐载体被封装在油脂凝中,在乳化后显示出更好的细菌活力.
科学领域:
- 食品科学与技术 食品科学与技术
- 生物技术是生物技术.
- 材料科学 材料科学 材料科学
背景情况:
- 由凝有机溶剂形成的油脂凝,提供不和脂肪酸和安全等优势.
- 基于天然油的油脂凝因其有益特性而受到越来越多的关注.
- 益生菌输送系统需要强大的封装来保持生存能力.
研究的目的:
- 开发含冷干燥的藻酸盐载体的油脂凝,其中包含益生菌Lactobacillus casei (L. casei) 的载体.
- 为了比较挤出与乳化技术的有效性,用于在油脂凝中进行益生菌封装.
- 评估封装方法对油脂凝内的益生菌生存能力的影响.
主要方法:
- 开发了两种油脂凝 (和糖凝),装有含有L. casei.的冷干燥酸盐载体.
- 生产带有益生菌的酸珠 (挤出,约1.2毫米) 和微球 (乳化,8-17微米).
- 评估封装效率和细菌活力在油中储存30天以上.
主要成果:
- 这两种方法都实现了高封装效率 (乳化:90%,挤出:87%).
- 与挤出珠子 (约1.2毫米) 相比,乳化产生了明显较小的微球 (8-17微米).
- 在使用通过乳化而不是挤出产生的微球的油脂凝中,细菌活力更高.
结论:
- 生产方法极大地影响了oleogel系统中的益生菌生存能力.
- 乳化是一种优质的技术,可以将L. casei封装在油脂凝中的酸盐载体中,从而确保更好的菌株存活.
- 开发的油脂凝显示出作为益生菌有效传递系统的潜力.
相关概念视频
Bioremediation
Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.
Microbial Bioremediation of Hydrocarbons
Bioremediation is an environmentally sustainable process that employs living organisms—primarily microorganisms—to degrade or neutralize pollutants from contaminated environments. In oil spills and hydrocarbon pollution, bioremediation involves the use of hydrocarbon-degrading bacteria to transform toxic compounds into less harmful substances. This approach leverages natural microbial metabolic processes and is considered both cost-effective and ecologically favorable compared to physical or...
Bioreactor Design and Operational System
Bioreactors are engineered vessels designed to cultivate microorganisms under controlled conditions for industrial bioprocessing. They maintain sterility and allow precise regulation of pH, temperature, oxygen, and nutrient levels to optimize microbial growth and metabolite production. Bioreactors range from small laboratory units of 1 liter to industrial systems holding up to 500,000 liters, though only about 75% of their volume is actively used for fermentation. The remaining headspace...
Production of Organic Acids
Lactic acid, an important organic acid extensively applied in food, pharmaceutical, and biodegradable polymer industries, is primarily produced via microbial fermentation. This method is favored over chemical synthesis due to its environmental sustainability and capacity for enantiomerically pure product formation. Among various microbial processes, the fermentation of starch-based substrates stands out due to the abundance and renewability of raw materials like corn and potatoes.Hydrolysis of...
Production of Antibiotics
Penicillin, one of the earliest and most widely used antibiotics, is produced industrially by the filamentous fungus Penicillium chrysogenum. Large stirred-tank bioreactors ranging from tens to hundreds of thousands of liters maintain tightly controlled temperature, pH, and dissolved oxygen conditions to support fungal metabolism and maximize antibiotic yield. Penicillin is a secondary metabolite, synthesized primarily during the stationary growth phase, which requires a carefully managed...
iChip
The cultivation of environmental microorganisms has long been hindered by the inability to replicate complex native conditions in vitro. The isolation chip (iChip) addresses this limitation by facilitating the growth of previously uncultivable microorganisms through in situ incubation. Designed for high-throughput microbial cultivation, the iChip comprises hundreds of microchambers, each capable of housing a single microbial cell. These microchambers are loaded with a mixture of molten agar and...

