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通过修改溶剂蒸发制备的多乳酸微球中有效封装和受控释放杀虫剂埃玛丁酸盐

Sheng Xu^1,2, Yamin Liu¹, Yilan Chen¹

¹School of Ecological Environment and Urban Construction, Fujian University of Technology, Fuzhou 350118, China.

Molecules (Basel, Switzerland)

|January 8, 2025

概括

新的聚乳酸 (PLA) 微球提供受控释放的乳母素酸 (EB),一种有效的杀虫剂. 与传统配方相比,这些环保的EB封装PLA微球显示出优越的害虫防治效果.

科学领域:

农业科学农业科学
材料科学材料科学材料科学
昆虫学昆虫学是一门学科.

背景情况:

埃马丁酸盐 (EB) 是一种强效的杀虫剂,但很容易降解,导致常规配方过度使用.
开发可控释放配方对于提高EB疗效和减少环境影响至关重要.

研究的目的:

开发和优化以聚乳酸 (PLA) 为基础的微球,用于控制释放乳母素酸 (EB).
为了评估EB载荷的PLA微球的物理化学特性,封装效率和受控释放行为.
为了比较带有EB的PLA微球对Plutella xylostella与常规EB配方的疗效.

主要方法:

用修改的溶剂蒸发方法来制备带EB的PLA微球.
优化了工艺参数,以提高封装效率 (EE) 和农药负载.
使用FTIR,DSC和XRD进行了物理化学表征.
在体内对Plutella xylostella的疗效进行了评估,并与商业EB乳化缩剂 (EC) 相比较.

主要成果:

优化EB载荷的PLA微球实现了高EE (90.63±1.90%) 和球形形态.
整合外部水相显著改善了EE超过30%.
FTIR,DSC和XRD证实了EB在PLA中的物理封装,没有化学降解.
与EB EC (19.23 ± 6.66%在14天后) 相比,EB装载的PLA微球对Plutella xylostella的校正死亡率 (90.00 ± 5.77%在21天后) 显著更高.

结论:

装有EB的PLA微球代表了对乳母丁酸盐有前途的受控释放配方.
这种配方提供了增强的害虫控制效果和减少环境影响的潜力.
开发的微球显示出强大的潜力,作为传统杀虫剂应用的环保替代品.

关键词:

有控制释放的释放.埃玛丁佐酸是一种这些微球是微球.改变了溶剂蒸发的方法.多乳酸多乳酸是什么意思

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