制造一个集成的,灵活的,无线压力传感器阵列,用于监测心室压力
Natiely Hernández-Sebastián1, Daniela Diaz-Alonso2, Bernardino Barrientos-García1
1Centro de Investigaciones en Óptica, A.C., CIO, Leon 37150, Mexico.
Micromachines
|January 8, 2025
概括
这项研究引入了一种灵活的无线电容式压力传感器,用于连续监测心室压力. 这种新型的可植入装置可以实现准确的远程测量,从而实现最少的侵入性手术.
科学领域:
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
- 电气工程 电气工程
背景情况:
- 对心室压力的持续监测对于诊断和管理心血管疾病至关重要.
- 现有的压力监测方法往往涉及侵入性程序或缺乏长期可靠性.
- 需要灵活,无线和生物相容的传感器来准确的体内压力传感.
研究的目的:
- 设计,制造和验证一个灵活的,无线的,电容式压力传感器,用于全程连续监测心室压力.
- 开发一种可植入的传感器系统,配有外部读取装置,用于被动的无线压力传感.
- 为了优化传感器的性能,使其具有广泛的压力范围和可靠的信号检索.
主要方法:
- 利用表面微加工和灵活的电子产品,在聚胺基板上创建一个双变量电容阵列和一个双层平面线圈.
- 将组件集成到一个灵活,生物相容,可折叠的植入式组件中.
- 使用印刷电路板 (PCB) 开发了一个外部读出设备,并使用控制式压力室和Maxwell-Wien桥梁电路验证了系统性能.
主要成果:
- 电容传感器显示电容变化从5.68 pF到33.26 pF,压力范围为0到300 mmHg.
- 反响频率从12.75 MHz转移到5.27 MHz,灵敏度为0.58 pF/mmHg,响应时间为220 ms.
- 实现了超过3.5厘米的无线传感距离,即使与错位,测量输出电压的低误差为±2.2 mV.
结论:
- 开发的灵活,无线电容式压力传感器适用于连续的心室压力监测.
- 生物相容和最少侵入性的设计使其在临床应用中更容易使用.
- 该系统的强大性能和长距离传感距离为先进的心血管监测提供了有前途的解决方案.
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