在Beta-Thalassemia患者中HEV感染
Despoina Papageorgiou1, Anne-Lise de Lastic2, Olga Tsachouridou3
1Medical School, University of Patras, Rio, 26504 Patras, Greece.
Pathogens (Basel, Switzerland)
|January 8, 2025
概括
肝炎E病毒 (HEV) 对血病患者构成风险,他们容易受到慢性感染和并发症的影响. 本综述考察了HEV的流行,风险因素和该人群的管理,以提高血液安全.
科学领域:
- 血液学 血液学 血液学
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
背景情况:
- thalassemia是一种遗传性血液疾病,影响全球蛋白链合成.
- 肝炎E病毒 (HEV) 引起急性病毒性肝炎,而亲肠传染是一种担忧.
- thalassemia患者患有严重的HEV感染和并发症的风险增加.
研究的目的:
- 审查血病患者中HEV感染的患病率.
- 在这个队列中识别与HEV感染相关的风险因素.
- 探索HEV在血病中的临床影响和管理策略.
主要方法:
- 文献综述专注于HEV流行率和沙拉西米亚.
- 分析风险因素,包括年龄,性别和输血史.
- 检查临床结果和治疗方法的HEV在血病患者.
主要成果:
- 在全球范围内,血病患者的HEV患病率各不相同.
- 血液输血史,年龄,性别和居住地区是已识别的风险因素.
- 在thalassemic个体中,HEV感染可能导致慢性肝炎和严重并发症.
结论:
- 警监测和血液捐献中的HEV查对于血病患者至关重要.
- 了解HEV风险对于防止这一脆弱群体出现严重后果至关重要.
- 实施预防措施可以提高血液安全性和患者保护.
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