澳大利亚老年人的代谢健康,超重或肥胖以及肺功能
Jacob Opio1, Katie Wynne1,2,3, John Attia1,3
1School of Medicine and Public Health, University of Newcastle, University Drive, Callaghan, NSW 2308, Australia.
Nutrients
|January 8, 2025
概括
较高的体重和代谢问题增加了老年人的限制性肺功能. 然而,肥胖与较少阻塞性肺模式有关.
科学领域:
- 老年学是指老年学的学科.
- 肺部病理学 肺部病理学
- 代谢健康 代谢健康
背景情况:
- 关于脂肪,代谢健康和肺功能之间的相互作用的研究有限.
- 本研究探讨了老年人中螺旋计肺功能和超重/肥胖之间的横截面关系,考虑了代谢状态.
研究的目的:
- 检查肺功能参数 (FEV1,FVC,FEV1/FVC比率) 与身体质量指数 (BMI) 分类之间的关联.
- 评估代谢健康如何影响老年人的这些关联.
主要方法:
- 利用了来自猎人社区研究队列的3318名老年人 (BMI ≥18.5 kg/m2) 的数据.
- 按BMI (肥胖度定义为BMI≥30 kg/m2) 和代谢健康 (国际糖尿病联合会标准) 分类参与者.
- 使用螺旋计评估肺功能,并将肺功能障碍分为限制性,阻塞性和混合型.
主要成果:
- 代谢健康的超重 (MHOW) 个体与代谢健康的正常体重 (MHNW) 个体相比,限制性肺部模式的几率增加 (OR=1.67).
- 与MHNW相比,MHOW和代谢不健康的超重 (MHO) 组的阻塞性 (OR=0.39,OR=0.36) 和混合性 (OR=0.39,OR=0.29) 肺部模式的几率较低.
- 肥胖与阻塞性肺功能模式相反相关.
结论:
- 体重指数升高和代谢健康变化与老年人患有限制性肺功能模式的更高患病率有关.
- 肥胖表明与阻塞性肺功能模式的反向关系,表明复杂的相互作用.
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