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维生素D补充时间对早期儿童发育里程碑的影响:一项回顾性研究
Andrea D Praticò1, Manuela Lo Bianco2, Roberta Leonardi3
1Unit of Pediatrics, Department of Medicine and Surgery, University Kore of Enna, 94100 Enna, Italy.
与六个月相比,将维生素D补充剂延长到十二个月,在婴儿发育里程碑 (如行走和说话) 中显示出适度但显著的改善. 需要进一步的研究来证实这些对幼儿发展的好处.
科学领域:
- 儿科发展 儿科发展
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 维生素D对于婴儿的骨,神经肌肉和神经发育至关重要.
- 儿童早期的发育依赖于足够的维生素D水平.
- 了解最佳的维生素D补充时间是关键.
研究的目的:
- 评估6个月对12个月维生素D补充剂对婴儿发育里程碑的影响.
- 根据补充剂的持续时间来比较运动,精细运动和社会里程碑的成就.
主要方法:
- 对209名婴儿进行了回顾性研究,分为6个月 (n=102) 和12个月 (n=107) 的维生素D补充组.
- 评估发展里程碑,包括坐着,走路,追踪物体,抓住,微笑和说话.
- 使用t测试和效果大小计算进行统计分析,以比较里程碑成就年龄.
主要成果:
- 12个月的维生素D组实现了步行,物体跟踪和短语形成显著更早.
- 两组之间没有观察到坐着或微笑的里程碑的显著差异.
- 重要里程碑的效果大小从小到中等.
结论:
- 长期服用维生素D补充剂 (12个月) 与婴儿发育中适度但显著的进步有关.
- 社会环境因素可能与维生素D一起影响发育结果.
- 建议进行前性研究,以确认发现并指导最佳婴儿补充方案.
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