在阴离子固化环氧复合材料中的In VitroHydroxyapatite核化与粉碎日种子
Muhammad Atif1, Dilawaiz1, Hafsah Akhtar2
1Chemistry Department, University of Education Lahore, Vehari Campus, Vehari 61100, Pakistan.
Polymers
|January 8, 2025
概括
枣种子粉 (DSP) 有效地促进酸 (HA) 的形成,用于骨再生应用. 经过修改的DSP复合材料显示出增强的抗菌特性,提供可持续的生物医学材料解决方案.
科学领域:
- 生物材料科学 生物材料科学
- 材料化学 材料化学
- 生物医学工程 生物医学工程
背景情况:
- 越来越多的人对从生物废弃物中获得可持续,成本效益高的生物材料感兴趣.
- 酸 (HA) 对于骨健康,强度和再生至关重要.
- 枣种子 (DS) 为材料开发提供了潜在的生物废物来源.
研究的目的:
- 调查日种子粉 (DSP) 对酸 (HA) 形成的影响.
- 评估基于DSP的复合材料在骨再生和抗菌应用中的潜力.
- 评估DS物理形式和表面修饰对HA核和性质的影响.
主要方法:
- 使用谷物和粉末形式的枣子种子制备DSP复合材料,有或没有表面修改.
- 在体外测试复合材料通过浸泡在模拟体液 (SBF).
- 使用X射线衍射 (XRD),红外里叶变换 (FTIR) 和热重力测量分析 (TGA) 的表征.
- 评估凝含量,水友性和抗菌活性.
主要成果:
- XRD和FTIR在所有浸泡SBF的样本中证实了HA的形成.
- 在浸泡样本中,TGA表明了更好的热稳定性,与更高的HA度相关.
- DSP复合材料具有高凝含量 (>90%) 和低水友性 (<5%),有利于HA核化.
- 与原始样本相比,添加日种子填充剂改善了抗菌活性,而修改样本显示出更好的结果.
结论:
- DSP是促进HA形成的可行的前体,对于骨组织工程至关重要.
- 基于DSP的复合材料在骨再生和增强抗菌功效方面显示出有前途的潜力.
- 对DSP的表面修改提高了其性能,突出了其作为可持续生物医学材料的实用性.
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